MALEGRA PRO-100

$6.13

CHARACTERISTICS
ACTIVE HALF-LIFE 4-6 HOURS
CLASSIFICATION PDE5 INHIBITOR
DOSAGE MEN 100 MG/DAY
ACNE NO
WATER RETENTION NO
HBR POSSIBLE
HEPATOTOXICITY NO
AROMATIZATION NO
ACTIVE SUBSTANCE SILDENAFIL
FORM 10 PILLS X 100 MG
MANUFACTURER SUNRISE REMEDIES

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Description

Chemical name: 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
Formula: C28H38N6O11S
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid

MALEGRA PRO-100

MALEGRA PRO-100 is a generic drug marketed by Sunrise Remedies Pvt. Ltd. It has sildenafil citrate as the main active pharmaceutical ingredient. It is commonly prescribed for the management of Erectile Dysfunction (ED) in men. ED is a condition whereby men are unable to achieve a satisfactory erection. It is one of the most common diseases of sexual disorders which can be easily managed on an outpatient basis. MALEGRA PRO-100-100 is a prescription only medication available in the strength doses of 50 and 100 mg. It has to be taken only after proper consultation with a doctor and, like all medications, has some adverse effects which can be minimized if certain precautions are taken. No doubt, the introduction of Sildenafil has revolutionized the treatment of ED, but over the years, different companies have released a myriad of generic brands and more data from clinical studies concerning Sildenafil have emerged. It is imperative to take all of this into consideration before choosing any particular brand of Sildenafil.

HOW IT WORKS:

Sildenafil citrate causes the inhibition of the enzyme phosphodiesterase type 5 (PDE5). In the erectile tissues of the penis, there is increased blood flow secondary to the release of cGMP and nitric oxide during sexual stimulation. This increased flow causes erection of the penile tissues. It is CGMP and nitric oxide that maintains the vasodilatation of the blood vessels, therefore, by inhibiting PDE5, cGMP remains longer in the blood and causes prolonged erection.

By relaxing the smooth muscles of blood vessels and maintaining blood flow to the penis, sildenafil ensures continued erection for a satisfactory sexual intercourse. It hence has a beneficial effect on men suffering from ED. For sildenafil to be effective, sexual arousal is necessary. Taking Sildenafil, at least 1 hour prior to any sexual activity, men with ED are able to maintain an erection. However, Sildenafil is a temporary treatment for ED, not a permanent cure.

DOSAGE:

Depending on the circumstances, the daily dose of MALEGRA PRO-100 can range from 25 mg to 100 mg. In cases of kidney and liver impairment or age more than 65 years, it is better to start with 25 mg after consultation with a doctor. Otherwise, a starting dose of 50-100 mg is acceptable. The maximum dose that should not be exceeded in 24 hours is 100mg.

It is to be noted that Sildenafil is used to control the symptoms of ED; it is not a cure. The duration of therapy is, therefore, depending on the patient’s discretion or development of side effects warranting discontinuation.

SIDE EFFECTS:

No drug is free from side effects. In the case of Sildenafil citrate, most side effects are secondary to vasodilatation in other organs of the body. The most frequently reported symptom is a headache followed by flushing of face and neck, dizziness, bleeding from nose, diarrhea and blurred vision. Fortunately, tolerance develops to most side effects with continued usage of the drug. Conversely, side effects which warrant urgent medical attention are chest pain, erection for more than 4 hours or sudden loss of vision.

Patients who have liver, heart or kidney diseases should take MALEGRA PRO-100 only after seeking proper medical opinion. Finally, those with anatomical deformity of the penis like Peyronie’s Disease should altogether avoid MALEGRA PRO-100.

DRUG INTERACTIONS:

It is strictly prohibited to consume Sildenafil along with other vasodilating agents, especially Nitrates like amyl nitrate and nitroglycerin. The synergistic effect of both drugs can cause dangerous and potentially fatal hypotension. Furthermore, people on antiviral therapy with protease inhibitors should also lower their usual dose of MALEGRA PRO-100. This is because protease inhibitors prolong the effect of Sildenafil in the body

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