Chemical name: 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
Malegra-120 is a promising generic drug produced by Sunrise Remedies for the treatment of erectile dysfunction. Men who have impotence use it on as needed basis. The recommended dosage of Malegra is 120mg. The effect of this drug lasts for 4 -6 hours. Malegra-120 brand is to be taken one hour before sexual intercourse. It is advisable to drink a glass of water while consuming. Also, Malegra-120 should not be taken with alcohol or fatty meals. The available dosage form of Malegra are pills and oral jelly. If you have liver or kidney diseases, you should not take erectile dysfunction drugs. In addition, the drug may interact with nitrates and isosorbides. The drug is not suitable for women and children. There are some side effects as a headache, gastric disturbances and nausea have been reported with Malegra 120. But these effects are mild and last for a few hours
HOW IT WORKS:
The physiology of erection is that nitric oxide activates the enzyme guanylate cyclase which causes an increase in cyclic guanosine monophosphate (cGMP). This enzyme causes erection by smoothing muscles of corpus cavernosum and allowing blood flow to the penis. Sildenafil is a potent inhibitor of phosphodiesterase type 5 (PDE5), which breaks down cGMP. In response to sexual stimulation, sildenafil causes an increase in cGMP resulting in relaxation of smooth muscle and flow of blood in the corpus cavernosum. Sildenafil does not work without sexual stimulation.
Malegr-120 contains sildenafil citrate which inhibits PDE-5. So, it causes full erection by causing a smooth in muscles in corps cavernosum and allows blood flow into the penis. Patients have noticed an improvement in erection and sexual intercourse. Now they enjoy sex with their partners.
The recommended dosage of Malegra is 120mg. You should take the drug one hour before sexual intercourse. It is advisable to drink a glass of water. Also, you should not take the drug with alcohol or fatty meals. If you have liver or kidney diseases, you should not take erectile dysfunction. The drug may interact with nitrates and isosorbides. The drug is not suitable for women and children. The effect of this medication lasts up to 4 -6 hours.
There are known side effects as a headache, gastric disturbances, and nausea that have been reported with Malegra-120. But these effects are mild and last for a few hours. In rare cases, chest pain, breath shortness, and painful erection may occur. Malegra-120 is not suitable for men suffering from arrhythmia, stroke, and myocardial infarction.
As for Malegra-120, it is not recommended to be taken with nitrates and isosorbide, as these drugs may interfere with the effectiveness of the product. The drug is not suitable for women and children. Also, diabetic patients should not use it.