Today, Shanghai CDC issued a notice: In the recent genetic sequencing monitoring of COVID-19 confirmed imported cases from the UK, the Novel Coronavirus gene sequence of one case was found to be subtype B.1.1.7, similar to the mutated virus gene reported in the UK recently.
The case, a Chinese national studying in the UK, left the UK on 13 December and arrived at Shanghai Pudong International Airport on 14 December. It was quarantined immediately after entering the customs.
A confirmed case (mild) of COVID-19 was diagnosed on 16 December.
At present, the case in the municipal public health clinical center isolation treatment, the condition is stable.
All passengers on the same flight of the case were put under quarantine for 14 days as required, and no abnormality was reported during the quarantine period.
At present, novel Coronavirus mutant strain with pathogenicity is reported in Britain
There is no obvious change, and the public need not panic
Xu Wenbo, director of the Institute of Viral Diseases of China CDC, was interviewed by reporters
- Has the transmissibility of the mutant found in Shanghai been enhanced?
The genetic test results of the strain found in Shanghai showed that the strain was more infectious to cells, but its transmissive ability was closely related to human social activities, winter climate and self-protection measures.
- Has the virus-causing power and severity of the mutant increased?
At present, there is no difference in pathogenicity, severity or mortality between novel Coronavirus variant strain and previous variant strain, and there is no obvious change in pathogenicity, so there is no need to panic.
- Does China’s COVID-19 vaccine have a protective effect on the mutant strain?
Novel Coronavirus variant strain has not been found to have any effect on the immune potency of inactivated novel coronavirus vaccine marketed in China.
- Can the nucleic acid test reagent of COVID-19 vaccine detect the mutant strain?
At present, the mainstream nucleic acid diagnostic reagent in China is novel Coronavirus dual-target gene, N gene and ORF1ab gene. The protein gene variation does not affect the sensitivity and specificity of the nucleic acid reagents. The Shanghai variant was detected by the native nucleic acid reagents in China.
- Are the existing prevention and control measures of novel Coronavirus transmission effective in China?
In April, China stopped the transmission of novel Coronavirus in its home country. After that, more than 10 novel Coronavirus pneumonia clusters caused by imported cases or contaminated cold chain items from abroad were all effectively interrupted.
Regular screening of high-risk groups, early diagnosis, early treatment, early isolation of infected persons and close contacts, wearing masks, frequent hand washing, and maintaining social distance;
It is an effective measure to block the transmission of novel Coronavirus.
- What further measures should be taken in response to the novel Coronavirus mutant mutant?
There is no need for people to panic, and the existing prevention and control measures in China must be strictly implemented. It is necessary to strengthen the awareness of personal protection, especially the protection of medical and staff in hospitals or hotels with imported cases.
After the news
According to a research report published by Chinese Center for Disease Control and Prevention on December 30, 2020, a mutation novel Coronavirus infection originally found in The UK was first reported in Mainland China.
China CDC Weekly
According to a research report published by the Chinese Center for Disease Control and Prevention on December 30, 2020, a mutation novel Coronavirus infection originally found in the UK was first reported in the Chinese mainland.
Screenshots from the China Daily report
According to a research report in the China CDC Weekly, the case is a 23-year-old female student who recently flew back to Shanghai from the UK and tested positive for novel Coronavirus on 14 December and was transferred to hospital for isolation the same night.
An epidemiological investigation showed that on December 12, two days before she flew back to China, she tested negative for the new coronavirus.
She recalled running in the park without a mask and eating and drinking while waiting to board a plane, all of which could have caused her to become infected, the report said.
Genetic sequencing on December 24 showed that the strain of the disease was different from a previously detected strain, and further studies confirmed that the patient had a variant of the virus previously found in the UK.
To minimize the risk of transmission of the mutated virus, Shanghai has taken a number of measures, including strengthening the tracing of close contacts of patients, the report said.
With the effective control of epidemic situation in China, the input of novel Coronavirus is still a great risk in epidemic prevention work in China.
Over the past few months, strict measures have been taken to prevent the virus from entering through incoming passengers and goods.
Official notification by WHO
Novel Coronavirus four variant cases
On the evening of 31 December 2020 local time, WHO officially announced the novel Coronavirus major variations since its emergence, including four variants.
From late January to early February, novel Coronavirus appeared a mutation of D614G.
By June 2020, this variant will become the novel Coronavirus type of major worldwide dissemination.
The variant is more infectious and transmissible than the original strain, but it does not cause more serious disease and does not affect the effectiveness of existing diagnostic, vaccine and other measures.
From August to September 2020, a novel coronavirus variant related to mink was discovered in Denmark, which was named “Cluster 5” by relevant department in Denmark.
This variant may reduce the scope and duration of immune protection after natural infection or vaccination, according to preliminary studies that are still being assessed.
So far, Denmark has only detected 12 human cases of the variant in September 2020, and the variant does not appear to have spread widely.
On 14 December 2020, a novel Coronavirus variant titled “VOC 202012/01” was reported in the UK, originally appearing in the south-east of England.
Preliminary studies have shown that the variant is more transmissible, but the disease severity and reinfection it causes have not changed, leaving most diagnostic tools unaffected.
As of 30 December 2020, 31 other countries and territories had found the variant.
On 18 December 2020, a novel Coronavirus variant with a mutation of N501Y was detected in South Africa and named “501y.v2” variant in South Africa, which is rapidly spreading in three provinces of South Africa.
Preliminary studies have shown that the variant is associated with a higher viral load and may increase infectiity, but there is no evidence that it causes more serious disease, and further investigation is needed to understand its impact on transmission, diagnosis, vaccines and so on.
As of 30 December 2020, the variant has been found in four countries other than South Africa.
The W.H.O. says all viruses change over time, and most of the mutations do not increase the virus’s infectiousness, sometimes even limiting its spread.
Who also stresses that although preliminary assessments show that the novel coronavirus mutation found in the UK and South Africa will not increase the severity of the disease, but will lead to a higher incidence of the disease, stricter public health measures are needed to control the spread of the virus.